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To minimize the possibility of overdosage or the event of dependence, limit the prescribing and dispensing of sedative-hypnotic barbiturates, to the amount demanded for that interval right up until the next appointment

pentobarbital will minimize the level or effect of dasatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

pentobarbital will decrease the level or influence of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.

pentobarbital will lower the level or effect of pimavanserin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Stay away from coadministration if possible. Keep track of for reduced pimavanserin efficacy. A rise in pimavanserin dosage may very well be wanted.

pentobarbital will lower the level or outcome of acalabrutinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

pentobarbital will reduce the level or outcome of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

pentobarbital will minimize the level or result of bedaquiline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Keep away from coadministration of bedaquiline with strong CYP3A4 inducers on account of opportunity for reduced therapeutic influence

The usage of barbiturates as sedatives within the postoperative surgical interval and as adjuncts to most cancers chemotherapy is nicely established

pentobarbital will lessen the level or outcome of quinidine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will lessen the level or result of bosentan more info by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.

pentobarbital will lessen the extent or effect of cannabidiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Consider an increase in cannabidiol dosage (determined by scientific reaction and tolerability) when coadministered with a solid CYP3A4 inducer.

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pentobarbital will minimize the level or influence of nelfinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will decrease the level or effect of ramelteon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.

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